文章摘要
不同镇痛方法用于髋部或股骨干骨折患者椎管内麻醉摆放体位时镇痛效果的网状Meta分析
Analgesic effects of different analgesic methods in patients with hip and femoral shaft fractures during spinal anesthesia position placement: a network meta-analysis
  
DOI:10.12089/jca.2024.01.013
中文关键词: 镇痛  神经阻滞  椎管内麻醉  体位  网状Meta分析
英文关键词: Analgesia  Nerve block  Spinal anesthesia  Position  Network meta-analysis
基金项目:甘肃省科技计划(创新基地和人才计划)(20JR10RA435);甘肃省科技计划(重点研发计划)(23YFFA0053)
作者单位E-mail
周婷 730000兰州市甘肃中医药大学第一临床医学院  
葛龙 兰州大学循证医学中心  
崔一阳 730000兰州市甘肃中医药大学第一临床医学院  
薛建军 甘肃省中医院麻醉科 xjjfei419@126.com 
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中文摘要:
      
目的:采用网状Meta分析系统评价不同镇痛方法用于髋部或股骨干骨折患者椎管内麻醉摆放体位时的镇痛效果。
方法:计算机检索PubMed、Cochrane Library、Web of Science、EMbase、中国生物医学文献数据库(CBM)、中国知网、维普、万方,检索时间为建库至2022年8月,纳入髋部或股骨干骨折患者摆放体位和椎管内麻醉时实施镇痛的随机对照研究。由两名研究员独立进行文献筛选、资料提取和偏倚风险评价,采用Stata 17.0和RevMan 5.3软件进行统计分析。
结果:共纳入28篇文献,患者1 773例。累计排序概率曲线下面积(SUCRA)显示,降低摆放体位时VAS疼痛评分PENG阻滞(94.4%)效果最佳,其次是FIB联合IVA(83.8%)和FIB(71.1%);降低椎管内麻醉时VAS疼痛评分PENG阻滞(98.2%)效果最佳,其次是FIB(71.1%)和FNB(55.6%);缩短椎管内麻醉操作时间PENG阻滞(84.1%)效果最佳,其次是FNB(70.7%)和FIB(68.5%);升高体位摆放质量评分PENG阻滞(99.1%)效果最佳,其次是FIB(73.1%)和FNB(52.9%)。
结论:神经阻滞或神经阻滞联合IVA可降低髋部或股骨干骨折患者体位摆放和椎管内麻醉时VAS疼痛评分、缩短麻醉操作时间和升高体位摆放质量评分。PENG阻滞对髋部或股骨干骨折患者摆放体位和椎管内麻醉时实施镇痛的效果最佳。
英文摘要:
      
Objective: To systematically evaluate the efficacy of different analgesic methods in relieving the pain in hip and femoral shaft fractures patients during spinal anesthesia position by using network meta-analysis.
Methods: The articals of randomized controlled trials (RCTs) that analgesia was performed in patients with hip and femoral shaft fractures during the spinal anesthesia position placement were retrieved from the following database from the establishment of the database to August 2022, PubMed, the Cochrane Library, Web of Science, EMbase, China Biology Medicine (CBM), CNKI, VIP, and Wanfang databases. Literature screening, data extraction and bias risk assessment were conducted by two researchers separately. Stata 17.0 and RevMan 5.3 software were used for statistical analysis.
Results: A total of 28 RCTs with 1 773 patients were included. The surface under the cumulative ranking (SUCRA) curve showed that and PENG block (94.4%) had the best effect on reducing the VAS pain score of placement position, followed by FIB combined with IVA (83.8%) and FIB (71.1%), and PENG block (98.2%) had the best effect on reducing VAS pain score during spinal anesthesia, followed by FIB (71.1%) and FNB (55.6%), and PENG block (84.1%) had the best effect on shortening the time of spinal anesthesia operation, followed by FNB (70.7%) and FIB (68.5%), and PENG block (99.1%) had the best effect on improving the quality of positioning, followed by FIB (73.1%) and FNB (52.9%).
Conclusion: Nerve blocks or the combination with IVA can reduce pain scores during position placement and spinal anesthesia, shorten anesthesia operation time, and improve quality of position placement in patients with hip and femoral shaft fractures. PENG block has the best analgesic effect in patients with hip or femoral shaft fractures during positioning and spinal anesthesia.
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