Dexamethasone is widely used in clinical treatment due to its anti-inflammatory, anti-allergic, and immunosuppressive properties. Additionally, dexamethasone can prevent and treat postoperative nausea and vomiting, play a positive role in reducing postoperative pain, lowering the incidence of pharyngitis caused by endotracheal intubation, and promoting gastrointestinal function recovery. Despite the wide range of benefits associated with dexamethasone, it carries the risk of inducing hyperglycemia and postoperative infections, especially in diabetic patients. Therefore, the use of dexamethasone as an adjuvant medication in the perioperative treatment of diabetic patients remains controversial. This article reviews the advantages of dexamethasone in the perioperative treatment of diabetic patients, the impact of dexamethasone on diabetic patients, and the controversies of dexamethasone in patients with diabetes, with the aim of providing a reference for clinical application. |