Objective: To investigate the correlation between oral frailty and POD in elderly patients undergoing non-cardiac surgery.
Methods: A total of 268 elderly patients, 115 males and 153 females, aged ≥65 years, BMI 14-36 kg/m2, ASA physical status Ⅱ or Ⅲ, undergoing elective non-cardiac surgery from February 2023 to July 2023 were selected. The oral frailty index-8 (OFI-8) was used to measure the oral frailty status of patients one day before surgery. The 3-minute delirium diagnostic scale (3D-CAM) was used to evaluate the occurrence of POD 1, 2, 3 days after surgery. The patients were divided into delirium group (POD group) and non-delirium group (non-POD group) according to whether POD occurred 3 days after surgery. Multivariate logistic regression model was used to analyze the relationship between oral frailty and POD.
Results: POD occurred in 61 patients (22.7%). Multivariate logistic regression analysis showed that postoperative use of analgesic pump (OR = 2.298, 95% CI 1.034-5.108, P = 0.041) and oral frailty (OR = 2.295, 95% CI 1.193-4.415, P = 0.012) are significantly correlated with the occurrence of POD, after adjusting for age, ASA physical status, hemoglobin, anesthesia time and infusion volume.
Conclusion: The incidence of postoperative POD in elderly patients with preoperative oral weakness is significantly increased undergoing non-cardiac surgery, and preoperative oral weakness is correlated with the occurrence of POD. |
