Objective: To explore the effects of multiple groups of acupoint pre-embedding thread on the autonomic nervous system and gastrointestinal function in patients undergoing gynecological laparoscopic surgery under general anesthesia. Methods: Sixty patients, aged 25-64 years, BMI 18.5-30.0 kg/m2, ASA physical status Ⅰ or Ⅱ, were selected for laparoscopic gynecological surgery under general anesthesia. Patients were divided into two groups using a random number table method: control group (group C) and acupoint thread embedding group (group M), 30 patients in each group. Patients in group M received thread embedding at 10 acupoints in 5 groups, including Neiguan, Sanyinjiao, Geshu, Jueyin, and Weishu on the day before surgery. Patients in group C did not undergo thread embedding at acupoints before surgery. The HR, MAP, normalized unit of low frequency (LF), normalized unit of high frequency (HF) and LF/HF were recorded at 5 minutes before anesthesia induction, immediately after tracheal intubation, immediately after establishing pneumoperitoneum, 10, 20, and 30 minutes after pneumoperitoneum, and when tracheal intubation was removed. Motilin and gastrin concentrations in serum were measured on the day before surgery and 24 hours after surgery. The time of first postoperative exhaust and defecation, as well as the occurrence of nausea and vomiting within 48 hours after surgery were recorded. Results: Compared with group C, the HR was significantly lower, and the MAP, the LF and LF/HF in group M were significantly reduced at 10, 20, and 30 minutes after pneumoperitoneum, while HF was significantly increased (P < 0.05). The first postoperative time of exhaust and defecation in group M was significantly shortened (P < 0.05), and the incidence of nausea and vomiting within 24 hours after surgery was significantly reduced (P < 0.05). The concentrations of motilin and gastrin in serum of group M were significantly increased 24 hours after surgery (P < 0.05). Conclusion: The combination of acupoints and pre-embedding thread can regulate the autonomic nervous function of patients undergoing gynecological laparoscopic surgery under general anesthesia, which is beneficial for the recovery of postoperative gastrointestinal function and improves the quality of rehabilitation. |