| The concept of the Bezold-Jarisch reflex (BJR) has experienced more than 100 years, which is that the left ventricular unmyelinated vagus nerve input receptors are stimulated by drugs or mechanical pull, the stimulation was then integrated by the vagus nerve afferent brain stem nucleus and transmitted to the vascular movement center to form vagal nerve output enhancement, leading to severe bradycardia, peripheral vasodatation, hypotension and even cardiac arrest, e.g, a cardiovascular inhibitory reaction.Although BJR is applied in clinical anesthesia, insufficient attention has been paid to it, resulting in absence of the mechanism analysis of related sudden severe bradycardia, hypotension, and even cardiac arrest in perioperative period. |
