Objective To observe the effects of labor analgesic with different speed of programmed intermittent epidural bolus (PIEB).
Methods A total of 163 term parturients with singleton received labor analgesia with PIEB, aged 20-35 years, BMI 21-29 kg/m2, ASA physical status Ⅰ or Ⅱ, were randomly divided into three groups: low speed group (group L, n=50), medium speed group (group M, n=55) and high speed group (group H, n=58), 74 patients in each group. Epidural catheters was placed at the L2-3 interspace with the subject in lateral position. Epidural solution was 0.1% ropivacaine and 0.5 μg/ml sufentanil, and the initial loading dose was 8-10 ml. Electronic pulse pump formula was consisted of 0.1% ropivacaine + 0.5 μg /ml sufentanil mix analgesia 100 ml. Parameters were set as follows: pulse dose 8 ml/time, interval 1 hour, PCA 6 ml, interval 20 minutes. The pulse speeds of groups L, M, and H were 200, 400, and 600 ml/h, respectively. The VAS pain score of contraction and epidural-related intrapartum fever (ERMF) were recorded before labor analgesia, 30 minutes, 1, 2, 3, and 4 hours after labor analgesia. Lower extremity motor block (modified Bromage score), total number of PCA compressions, effective times of PCA compressions, total amount of local anesthetics and analgesic time were recorded.
Results There were no significant difference in VAS pain score of contraction and incidence of ERMF among the three groups at different time points. The modified Bromage scores in the three groups were all 0, and no motor block occurred. There were no significant differences in the total number of PCA compressions, effective number of PCA compressions, total amount of local anesthetics and analgesic time among the three groups.
Conclusion There is no significant difference in the effect of labor analgesia at different speeds of PIEB. |
