文章摘要
术后谵妄评估和预测的研究进展
Research progress in evaluation and prediction of postoperative delirium
  
DOI:10.12089/jca.2023.01.019
中文关键词: 术后谵妄  预测指标  评估方法
英文关键词: Postoperative delirium  Predictive indicator  Assessment method
基金项目:科技创新2030—“脑科学与类脑研究”重大项目(2021ZD0204302-2);北京大学第三医院临床重点项目(BYSYZD2021013)
作者单位E-mail
康猛 100191,北京大学第三医院麻醉科  
韩永正 100191,北京大学第三医院麻醉科 hanyongzheng@bjmu.edu.cn 
郭向阳 100191,北京大学第三医院麻醉科  
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中文摘要:
      术后谵妄(POD)是手术患者常见的并发症,严重影响患者远期认知功能、生理功能和社会功能。既往对POD的评估多以量表为基础,评估结果存在主观性,如何科学客观地进行POD的评估值得深入探究。POD可在早期预测并干预,从而进行有效预防,基于临床预测模型进行POD的风险预测已成为研究热点。本文从神经心理学量表、血清标志物、脑脊液标志物和脑电标志物等多个维度对POD的评估方法进行归纳,并针对POD临床预测模型的预测对象与预测指标进行总结,以期为POD评估和预测提供科学、可行、有效的参考依据。
英文摘要:
      Postoperative delirium (POD) is a common complication in patients undergoing surgery, seriously affecting long-term cognitive function, physiological and social function. Previous evaluations of POD were mostly based on scales, which makes the results to be influenced by subjectivity. It is worthy of exploring how to evaluate POD scientifically and objectively. POD can be predicted early and prevented effectively. The prediction of risk of POD based on clinical prediction model has become a research hotspot. This paper summarizes the evaluation methods of POD from multiple dimensions, such as neuropsychological scale, serum markers, cerebrospinal fluid markers and EEG markers, and summarizes the predictive objects and indicators of POD clinical prediction model, in order to provide a scientific, feasible and effective reference basis for POD evaluation and prediction.
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