Ojective To compare the effects of superposition high-frequency jet ventilation (SHFJV) and intermittent positive pressure ventilation (IPPV) on surgical field quality in patients undergoing functional endoscopic sinus surgery (FESS). Methods Eighty patients, 49 males and 31 females, aged 18-64 years, BMI 19-30 kg/m2, ASA physical statusⅠ-Ⅲ, who underwent FESS were selected. The patients were randomly divided into SHFJV group (group SH) and IPPV group (group IP), 40 cases in each group. Intraoperative crystalloid fluid, colloidal fluid, red blood cell (RBC), fresh frozen plasma (FFP), blood loss, urine volume, vasoactive drugs (nitroglycerin, norepinephrine) during maintenance, operation time were recorded. HR, MAP, cardiac index (CI), heart rate and blood pressure product (RPP), and surgical field quality scores were recorded every 15 minutes during surgery. pH, PaO2, PaCO2, SpO2, lactate (Lac), alkali surplus (BE), and Hb were recorded immediately after intubation, 1 hour, 2 hours after nasal endoscopy insertion, and at the end of operation. The incidence of chills, hypotension, nausea and vomiting, fever, sleep disorders, surgical site infection and pulmonary infection within 3 days after operation were recorded. Results Compared with group IP, the amount of blood loss, crystalloid fluid, colloid fluid, RBC infusion volume and RPP in group SH were significantly decreased (P < 0.01), the surgical field quality score was significantly decreased (P < 0.01), the pH was significantly decreased 1 hour, 2 hours after implantation, and the PaCO2, BE, and Hb were significantly increased (P < 0.05). PaCO2, BE, and Hb were significantly increased at the end of operation (P < 0.05), and the incidence of hypotension, nausea and vomiting were significantly decreased within 3 days after operation (P < 0.05). There was no significant difference in the incidence of chills, fever, sleep disturbance and pulmonary infection between the two groups. There was no infection of surgical incision in the two groups. Conclusion Compared with intermittent positive pressure ventilation, superposition high-frequency jet ventilation can reduce intraoperative blood loss, improve surgical field quality, reduce postoperative complications such as hypotension, nausea and vomiting in patients undergoing functional endoscopic sinus surgery, which is safe and effective in clinical practice. |