Objective To identify the risk factors of delayed extubation of endotracheal catheter following renal transplantation.
Methods A retrospective study was conducted on 366 patients who undergoing renal transplantation under general anesthesia from January 2017 to December 2020, 261 males and 105 females, aged 18-64 years. According to whether the extraction time of endotracheal catheter was more than one hour, the patients were divided into routine group and delayed group. Univariate analysis and multivariate Logistic regression analysis were used to identify risk factors of delayed extubation following renal transplantation.
Results There were 80 patients (21.9%) in the delayed group. Univariate analysis showed that compared with the routine group, in delayed group, the proportion of male and the number of relative living donor transplants were significantly increased (P < 0.05), preoperative Hb and blood calcium were significantly decreased (P < 0.05), cold ischemia time and anesthesia time were significantly prolonged (P < 0.05), induction of rocuronium and intraoperative blood transfusion were significantly increased (P < 0.05). Total fluid volume and blood loss were significantly increased (P < 0.05), extubation time and PACU residence time were significantly prolonged (P < 0.05). Multivariate Logistic regression analysis showed that preoperative Hb < 113 g/L (OR = 1.847, 95% CI 1.076-3.171, P = 0.026), preoperative serum calcium < 2.48 mmol/L (OR = 2.293, 95% CI 1.258-4.179, P = 0.007), cold ischemia time > 10.5 hours (OR = 1.986, 95% CI 1.139-3.464, P = 0.016), total fluid volume > 1 975 ml (OR = 3.092, 95% CI 1.795-5.324, P < 0.001) were independent risk factors of delayed extubation following renal transplantation.
Conclusion Preoperative Hb < 113 g/L, preoperative serum calcium < 2.48 mmol/L, and cold ischemia time > 10.5 hours, total fluid volume > 1 975 ml are independent risk factors for delayed extubation following kidney transplantation. |
