文章摘要
颊针在老年患者腹腔镜胆囊切除术中的效果
Effect of buccal acupuncture in elderly patients undergoing laparoscopic cholecystectomy
  
DOI:10.12089/jca.2022.01.006
中文关键词: 颊针  老年  腹腔镜胆囊切除术  应激反应
英文关键词: Buccal acupuncture  Aged  Laparoscopic cholecystectomy  Stress response
基金项目:国家自然科学基金(81671880);江苏省医学创新团队(CXTDA2017043);苏州市科研基金(LCZX201603);江苏省第五期“333高层次人才培养工程”科研项目基金(BAR2018261)
作者单位E-mail
苏丹 224000,江苏省盐城市第三人民医院麻醉科  
吉林 224000,江苏省盐城市第三人民医院麻醉科  
刘思兰 苏州大学附属第一医院麻醉手术科 szliusl@126.com 
嵇富海 苏州大学附属第一医院麻醉手术科  
申海斌 苏州大学附属第一医院麻醉手术科  
陆香红 苏州大学附属第一医院麻醉手术科  
孟晓文 苏州大学附属第一医院麻醉手术科  
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中文摘要:
      
目的 探讨颊针在老年患者腹腔镜胆囊切除术(LC)中的应用效果。
方法 选择择期行LC的老年患者97例,男55例,女42例,年龄65~74岁,BMI 20~30 kg/m2,ASA Ⅰ—Ⅲ级。采用随机数字表法将患者分为两组:对照组(n=48)和颊针组(n=49)。麻醉诱导前,颊针组给予颊针疗法,一直带针,每隔5 min行针一次,持续至手术结束。对照组不行颊针治疗。记录入手术室时(T0)、麻醉后5 min(T1)、手术切皮时(T2)、拔除气管导管后5 min(T3)、术后6 h(T4)、术后24 h(T5)的MAP和HR。记录术中丙泊酚、瑞芬太尼用量。于T0、T5时采集静脉血,检测血浆C反应蛋白(CRP)、皮质醇(Cor)、血糖和乳酸浓度。记录术后首次出现疼痛时间、术后24 h内补救镇痛例数、术后恶心呕吐(PONV)及术后肩部不适的发生情况。
结果 T2、T4时颊针组MAP明显低于对照组,HR明显慢于对照组(P<0.05)。颊针组术中丙泊酚、瑞芬太尼用量明显少于对照组(P<0.05)。与T0时比较,T5时对照组CRP、Cor、血糖、乳酸浓度明显升高(P<0.05),颊针组血糖浓度明显升高(P<0.05)。T5时颊针组CRP、Cor、乳酸浓度明显低于对照组(P<0.05)。颊针组术后首次出现疼痛时间明显长于对照组,术后24 h内补救镇痛比例、PONV及术后肩部不适发生率明显低于对照组(P<0.05)。
结论 在老年患者腹腔镜胆囊切除术中运用颊针疗法,有助于缓解术中及术后疼痛,降低应激反应程度,可作为老年患者手术麻醉的辅助方法。
英文摘要:
      
Objective To investigate the application effect of buccal acupuncture in the laparoscopic cholecystectomy for elderly patients.
Methods Ninety-seven elderly patients for laparoscopic cholecystectomy, 55 males and 42 females, aged 65-74 years, BMI 20-30 kg/m2, ASA physical status Ⅰ-Ⅲ, were randomly divided into two groups by random number table method: control group (n = 48) and acupuncture group (n = 49). The acupuncture group was given buccal acupuncture before induction of anesthesia, and the needle was performed every 5 minutes for the entire operation period. The control group was not be treated with buccal acupuncture. MAP and HR were recorded at the time when the patient entered the operating room (T0), 5 minutes after anesthesia (T1), skin incision (T2), 5 minutes after airway catheter removal (T3), 6 hours after surgery (T4), and 24 hours after surgery (T5). The dosage of intraoperative propofol and remifentanil were recorded. Venous blood samples were collected at T0 and T5, and plasma levels of C-reactive protein (CRP), cortisol (Cor), blood glucose and lactic acid were measured. The time when the patient first experienced pain after surgery, the proportion of additional analgesia required within 24 hours after surgery, the incidence of postoperative nausea and vomiting (PONV), and the incidence of postoperative shoulder discomfort were recorded.
Results MAP and HR in the acupuncture group were significantly lower than those in the control group at T2 and T4 (P < 0.05). The intraoperative dosage of propofol and remifentanil in the acupuncture group were significantly lower than those in the control group (P < 0.05). Compared with T0, the plasma levels of CRP, Cor, blood glucose, and lactate acid in the control group were significantly increased at T5, while the blood glucose concentration in the acupuncture group increased significantly at T5(P < 0.05). The levels of CRP, Cor and lactic acid in the acupuncture group were significantly lower than those in the control group at T5 (P < 0.05). The time of postoperative pain in control group appeared significantly earlier, and the proportion of additional analgesia needed was also significantly increased than that in the acupuncture group (P < 0.05). The incidence of PONV and shoulder discomfort in the acupuncture group was significantly less than that in the control group (P < 0.05).
Conclusion The application of buccal acupuncture in laparoscopic cholecystectomy for elderly patients can help to relieve pain during and after the operation, and reduce stress response. It can be used as an auxiliary method for anesthesia in elderly patients with LC.
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