Objective To evaluate the effect of ultrasound-guided sub-serratus anterior plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy.
Methods Sixty patients scheduled for percutaneous nephrolithotomy under general anesthesia, 38 males and 22 females, aged 22-64 years, BMI 18-26 kg/m2, ASA physical status Ⅰ or Ⅱ, were randomly divided into general anesthesia group (group C) and general anesthesia with sub-serratus anterior plane block group (group T), 30 patients in each group. In group T, ultrasound-guided sub-serratus anterior plane block was performed and 25 ml of 0.3% ropivacaine was given. Anesthesia maintenance was performed by total intravenous anesthesia with propofol and remifentanil. When VAS pain score ≥ 4 points, tramadol 100 mg intramuscular injection was given. The dosage of propofol and remifentanil during operation, VAS pain score and the number of analgesic remedy 30 minutes after extubation, 2, 6, 12, and 24 hours after surgery, and adverse reactions 24 hours after surgery were recorded.
Results Compared with group C, the dosage of remifentanil, VAS score 30 minutes after extubation, 2, 6, and 12 hours after surgery, nausea and vomiting in group T were decreased (P < 0.05). The analgesic remedy rate of group C was significantly higher than that in group T 24 hours after surgery (P < 0.05). There was no significant difference in the dosage of propofol between the two groups. There were no adverse reactions such as local anesthetic intoxication, pneumothorax, hematoma, and respiratory depression in two groups.
Conclusion Ultrasound-guided sub-serratus anterior plane block for percutaneous nephrolithotomy can reduce the dosage of opioids during operation and provide effective analgesia 12 hours after surgery with less adverse reactions. |
