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| 帕洛诺司琼联合揿针刺激足三里穴、内关穴预防妇科腹腔镜术后恶心呕吐的效果 |
| Effect of palonosetron combined with press needle acupuncture at Zusanli and Neiguan points on preventing postoperative nausea and vomiting after gynecological laparoscopic surgery |
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| DOI：10.12089/jca.2021.05.011 |
| 中文关键词: 帕洛诺司琼 揿针 足三里穴 内关穴 术后恶心呕吐 腹腔镜 |
| 英文关键词: Palonosertron Press needle Zusanli point Neiguan point Postoperative nausea and vomiting Laparoscopy |
| 基金项目: |
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| 中文摘要: |
目的 观察帕洛诺司琼联合揿针刺激足三里穴、内关穴对妇科腹腔镜术后恶心呕吐的预防效果。
方法 选择2020年4—8月择期全麻下行妇科腹腔镜手术的患者90例，年龄18~60岁，BMI 18~28 kg/m2，ASA Ⅰ或Ⅱ级，Apfel评分≥3分。采用随机数字表法将患者分为三组：帕洛诺司琼组（P组）、揿针刺激穴位组（Q组）和帕洛诺司琼联合揿针刺激穴位组（PQ组），每组30例。P组术前30 min静注帕洛诺司琼0.25 mg；Q组术前30 min揿针刺激双侧足三里穴、内关穴；PQ组术前30 min静注帕洛诺司琼0.25 mg联合揿针刺激双侧足三里穴、内关穴。记录术后0~3、3~6、6~12、12~18、18~24 h恶心呕吐严重程度和术后首次肛门排气、排便时间。
结果 术后3~6、6~12、12~18、18~24 h PQ组恶心呕吐严重程度明显低于P组和Q组，术后0~3、3~6、6~12、12~18、18~24 h P组和Q组间恶心呕吐严重程度差异无统计学意义。P组术后首次肛门排气、排便时间明显长于Q组和PQ组（P<0.05），Q组和PQ组差异无统计学意义。
结论 帕洛诺司琼联合揿针刺激足三里穴、内关穴对术后恶心呕吐有很好的预防和治疗作用，有助于患者术后胃肠功能的恢复。 |
| 英文摘要: |
Objective To observe the preventive effect of palonosetron combined with press needle stimulation at Zusanli and Neiguan points on postoperative nausea and vomiting after gynecological laparoscopic surgery.
Methods Ninety patients underwent gynecological laparoscopic surgery under general anesthesia, aged 18-60 years, BMI 18-28 kg/m2, ASA physical status Ⅰ or Ⅱ, Apfel score ≥ 3 points, were randomly divided into 3 groups: palonosetron group (group P), press needle acupoint stimulation group (group Q), and palonosetron combined with press needle acupoint stimulation group (group PQ), 30 patients in each group. Group P was treated with palonosetron 0.25 mg 30 minutes before operation, group Q was given acupoint pressing treatment of bilateral Zusanli and Neiguan points 30 minutes before operation, group PQ was given palonosetron 0.25 mg combined with bilateral Zusanl and Neiguan pressing points 30 minutes before operation. The degree of postoperative nausea and vomiting 0-3, 3-6, 6-12, 12-18, and 18-24 hours after operation, the first time of exhaust and defecation postoperation were all recorded.
Results The degree of postoperative nausea and vomiting 3-6, 6-12, 12-18, and 18-24 hours after operation in group PQ was significantly lower than that in groups P and Q (P < 0.05). There were no differences in degree of postoperative nausea and vomitting 0-3, 3-6, 6-12, 12-18, and 18-24 hours after operation between groups P and Q. The first time of exhaust and defecation postoperation in group P were significantly longer than those in groups Q and PQ (P < 0.05). There were no differences in the first time of exhaust and defecation postoperation between groups Q and PQ.
Conclusion Palonosetron combined with pressing needle stimulation of Zusanli and Neiguan points has a good preventive and therapeutic effect on postoperative nausea and vomiting, which is helpful to the recovery of gastrointestinal function after operation. |
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