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| 全麻患者围术期中心静脉血糖与手指末端血糖的相关性 |
| Relationship between central venous blood glucose and peripheral blood glucose under intravenous-inhalation combined anesthesia |
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| DOI：10.12089/jca.2019.12.009 |
| 中文关键词: 中心静脉 指尖毛细血管 血糖 全身麻醉 |
| 英文关键词: Central venous Fingertip capillary Blood glucose General anesthesia |
| 基金项目: |
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| 中文摘要: |
目的 探讨全麻患者围术期中心静脉血糖(CVG)与手指末端血糖(PBG)的相关性。
方法 本研究选择开放中心静脉通路的全身麻醉手术患者68例,男43例,女25例,年龄18～85岁,ASA Ⅰ-Ⅲ级。分别在麻醉前(T0)、麻醉诱导后5 min(T1)、手术开始30 min(T2)、手术结束即刻(T3)采血测定CVG和PBG,并计算两者差值ΔBG=CVG-PBG。采用Bland-Altman分析CVG与PBG的一致性；两者的相关性采用Pearson相关分析。
结果 Bland-Altman分析显示T0-T3四个时点中,每个时点均有3个(4.4％)检测值位于一致性界限（LoA）范围外,CVG与金标准PBG保持一致性,且CVG与PBG呈高度相关(T0:r=0.938,P<0.001;T1:r=0.815,P<0.001;T2:r=0.845,P<0.001;T3:r=0.906,P<0.001)。T1-T3时CVG均明显高于PBG(P<0.001);T0-T2时CVG明显低于T3时(P<0.001);T1、T2时PBG明显低于T0和T3时(P<0.001);T1-T3时ΔBG明显高于T0时(P<0.001)。
结论 在静-吸复合全身麻醉中CVG与PBG存在高度线性正相关,CVG或可代替PBG。 |
| 英文摘要: |
Ojective To explore the correlation between central venous and peripheral blood glucose patients under general anesthesia.
Methods A total of 68 patients, aged 18-85 years, ASA physical status Ⅰ-Ⅲ, elective surgical procedures with central vena catheterization under general anesthesia were included Central venous blood glucose (CVG) and peripheral blood glucose (PBG) were detected before anesthesia (T0), 5 min after anesthesia induction (T1), 30 min after surgery beginning (T2) and immediately after the operation (T3). The difference between CVG and PBG (ΔBG) was calculated. Pearson correlation coefficient and Bland-Altman analysis were used to investigate the relationship between CVG and PBG.
Results Bland-Altman analysis showed 3 of 68 were out of limits of agreement (LoA) at T0-T3 four time points with a ratio of 4.4％, which demonstrated that CVG was consistent with PBG, and at these four time points, CVG was correlated especially with PBG (T0: r = 0.938, P < 0.001; T1: r = 0.815, P < 0.001; T2: r = 0.845, P < 0.001; T3: r = 0.906, P < 0.001). At T1-T3 time points, CVG was higher than PBG (P < 0.001); and CVG at T0-T2 was lower than T3(P<0.001); PBG at T1, T2 was lower than at T0 and T3(P < 0.001); and the differences between CVG and PBG (ΔBG) at T1-T3 were higher than at T0(P < 0.001).
Conclusion CVG is correlated especially with PBG of patients, which may provide a theoretical basis for replacing CVG with PBG during perianesthesia clinically. |
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