文章摘要
妊娠合并肺动脉高压剖宫产患者围术期管理回顾
A retrospective analysis of perioperative management of pregnancy with pulmonary arterial hypertension undergoing cesarean section
  
DOI:10.12089/jca.2018.11.003
中文关键词: 妊娠  肺动脉高压  麻醉  围术期
英文关键词: Pregnancy  Pulmonary arterial hypertension  Anesthesia  Perioperative period
基金项目:
作者单位E-mail
苑雨辰 100730,中国医学科学院,北京协和医院麻醉科  
车璐 100730,中国医学科学院,北京协和医院麻醉科  
黄宇光 100730,中国医学科学院,北京协和医院麻醉科 garybeijing@163.com 
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中文摘要:
      
目的 探讨妊娠合并肺动脉高压患者行剖宫产手术的结局。
方法 回顾性分析2006年1月至2016年12月间就诊于本院的妊娠合并肺动脉高压并且行剖宫产手术的52例患者临床资料, 年龄21~41岁, ASA Ⅱ—Ⅳ级。搜集并记录患者基线数据、围术期药物使用、产后1月及1年时生存情况, 并进行回顾性队列研究。
结果 近10年来妊娠合并肺动脉高压且行剖宫产手术患者52例, 术后1月随访37例, 术后1年随访34例, 1月内和1年内死亡病例分别为4例(10.81%)和6例(17.65%); 影响患者预后的主要因素为肺动脉高压严重程度和术前SpO2水平。年龄、孕周、麻醉方式、围术期抗凝药物、术中监测等对患者围术期和术后1年生存率无明显影响。
结论 早期发现和控制肺动脉高压仍是改善预后的重要手段。
英文摘要:
      
Objective To investigate the outcome of pregnant women with pulmonary arterial hypertension who underwent cesarean section.
Methods Clinical data of 52 pregnant women with pulmonary arterial hypertension who underwent cesarean section in our clinical center from January 2006 to December 2016, aged 24 - 41 years, ASA physical status Ⅱ - Ⅳ, were analyzed retrospectively. Patients′ baseline data, perioperative medication, 1-month and 1-year survival were recorded and a retrospective cohort study was performed.
Results Fifty-two pregnant women with pulmonary arterial hypertension who underwent cesarean section were followed up in the past 10 years. Thirty-seven cases were followed up 1 month after surgery, and 34 cases followed up 1 year after surgery. The death rate was 4/37 (10.81%) at 1 month after surgery and was 6/33 (17.65%) at 1 year after surgery. The risk factors of the death of puerperants were pulmonary arterial hypertension severity and level of preoperative oxygen saturation. Age, gestational age, mode of anesthesia, perioperative anticoagulant drugs had no significant effect on the outcome of puerperants.
Conclusion Early detection and control of pulmonary hypertension is important to improve prognosis.
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