文章摘要
全麻患者气管插管套囊压力和术后气道并发症的现况调查及影响因素分析
Analysis of influencing factors ofendotracheal tube cuff pressure and postoperative airway complications in patients with general anesthesia
  
DOI:10.12089/jca.2018.08.001
中文关键词: 套囊压力  气道并发症  现况调查  危险因素
英文关键词: Endotracheal tube cuffpressure  Airway complications  Current situation investigation  Risk factor
基金项目:石河子大学成果转化与技术推广项目(CGZH201713)
作者单位E-mail
赵桂华 832000,新疆石河子大学医学院第一附属医院麻醉科  
翟晶雯 832000,新疆石河子大学医学院第一附属医院麻醉科  
徐江叶 新疆生产建设兵团第五师医院麻醉科  
张印龙 832000,新疆石河子大学医学院第一附属医院麻醉科  
葛明月 832000,新疆石河子大学医学院第一附属医院麻醉科  
殷姜文 832000,新疆石河子大学医学院第一附属医院麻醉科  
王胜 832000,新疆石河子大学医学院第一附属医院麻醉科 iamsheng2006@163.com 
代志刚 832000,新疆石河子大学医学院第一附属医院麻醉科  
董希玮 新疆生产建设兵团总医院麻醉科  
徐桂萍 新疆维吾尔自治区人民医院麻醉科  
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中文摘要:
      
目的 调查新疆地区全麻患者气管插管套囊压力及术后插管相关并发症的现状,并分析引起不适套囊压力的影响因素。

方法 采用整群抽样及单纯随机抽样方法,抽取2017年2—5月新疆地区3家三级甲等医院拟行全身麻醉气管插管并符合纳入标准的患者作为研究对象。登记相关信息,于气管插管后采用一次性压力换能器测量套囊压力,拔管后24 h内随访患者,记录术后气管插管相关并发症的发生情况。根据测压结果将患者分为套囊压力正常组(20~30 cmH2O)与套囊压力异常组(<20 cmH2O或>30 cmH2O),通过Logistic回归分析引起套囊压力过高或过低的危险因素。

结果 共纳入研究对象430例,气管导管套囊压力为(53.3±20.5)cmH2O,仅有82例(19.1%)患者套囊压力在推荐范围。术后气道并发症主要有:咽喉痛305例(70.9%),声音嘶哑159例(37.0%),咳嗽147例(34.2%),血丝痰145例(33.7%)。Logistic回归分析显示,BMI≥27 kg/m2(OR=11.000,95%CI 1.064~113.731)、术前气道特殊情况(吸烟、哮喘等,OR=2.809,95%CI 1.300~6.070)、麻醉科医师职称(住院医师,OR=60.224,95%CI 18.853~192.380;主治医师,OR=7.364,95%CI 3.112~17.426)和工龄(≤5年,OR=68.500,95%CI 15.253~307.619;6~10年,OR=10.400,95%CI 4.430~24.417)是导致患者出现不适套囊压力升高的危险因素。

结论 临床工作中套囊压力远高于推荐值,插管相关并发症发生率高,而术前患者肥胖、有吸烟史或合并哮喘、气管炎,麻醉科医师职称较低、工作时间较短是导致气管导管套囊压力异常的危险因素。
英文摘要:
      
Objective To explore the current situation of endotracheal tube cuff pressure and postoperative intubation-related complications in patients under general anesthesia, and to analyze the influencing factors for excessive and insufficient cuff pressure.

Methods The patients who met inclusion criteria in three hospitals in Xinjiang province, scheduled for surgery under general anesthesia with endotracheal intubation from February to May 2017 were selected using cluster sampling method and simple random sampling method. The cuff pressure was measured using a traditional pressure transducer after intubation. The patients were followed-up 24 h after extubation to observe postoperative intubation-related complications. In accordance with the measured cuff pressure, 82 patients were regarded as normal cuff pressure group and 348 patients were designated as abnormal cuff pressure group. Comparison of clinical data between the two groups and multivariable logistic regression analysis were performed to predict the risk factors of excessive and insufficient cuff pressure.

Results A total of 430 patients were included in the study. The measured pressure was (53.3 ± 20.5) cmH2O, and only 82 patients had a cuff pressure within the recommended range of 20-30 cmH2O with a probability of 19.1%. Cases and incidences of sore throat, hoarseness, cough, and blood-streaked expectorant after operative was 305 (70.9%), 159 (37.0%), 147 (34.2%), and 145 (33.7%), respectively. Multivariate logistic regression analysis demonstrated that BMI ≥27 kg/m2 (OR=11.000, 95% CI 1.064-113.731), smoking history, asthma, or bronchitis history (OR=2.809,95% CI 1.300-6.070) in patients and the title of anesthesiologists (resident, OR=60.224, 95% CI 18.853-192.380) who inflated the cuff and their working years (≤5 years, OR=68.500, 95% CI 15.253-307.619;6-10 years, OR=10.400, 95%CI 4.430-24.417) were the independent risk factors of improper cuff pressure.

Conclusion Cuff pressure is much higher than the recommended range in clinical practice and the incidence of intubation-related complications is quite high. Preoperative obesity, smoking history, asthma, or bronchitis history of patients, lower professional title and shorter working years of anesthesiologists are risk factors of abnormal endotracheal tube cuff pressure.
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