文章摘要
不同压力CO2气腹对妇科腹腔镜手术患者术后胃肠道功能的影响
Effect of different pressure CO2 pneumoperitoneum on postoperative gastroeuteric function in female patients undergoing gynecological laparoscopic surgery
  
DOI:10.12089/jca.2018.04.011
中文关键词: 气腹  腹腔镜  妇科手术  胃肠道功能
英文关键词: Pneumoperitoneum  Laparoscopy  Gynecological surgery  Gastrointestinal function
基金项目:安徽医科大学校科研基金资助项目(2015xkj150)
作者单位E-mail
李雨霏 246000,安徽医科大学附属安庆医院麻醉科  
王胜斌 246000,安徽医科大学附属安庆医院麻醉科 shbw1965@126.com 
居霞 246000,安徽医科大学附属安庆医院麻醉科  
胡胜红 246000,安徽医科大学附属安庆医院麻醉科  
徐四七 246000,安徽医科大学附属安庆医院麻醉科  
李元海 安徽医科大学第一附属医院麻醉科  
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中文摘要:
      目的 探讨不同压力CO2气腹对妇科腹腔镜手术患者术后胃肠道功能的影响。方法 择期行妇科腹腔镜手术患者120例,年龄30~60岁,ASA Ⅰ或Ⅱ级。采用随机数字表法将患者分为三组,每组40例。L组、M组和H组气腹压力分别为6~8、9~11和12~14mm Hg。所有患者检测术前6 h、术后6 h检测患者空腹血清D-乳酸含量,记录麻醉诱导前(T1)、气腹前(T2)、气腹后1 h(T3)、2 h(T4)及停止气腹后1 h(T5)的动脉血pH、PaCO2和PaO2。记录术中气腹时间,术后首次排气时间、进食时间、排便时间、术后住院时间。结果 三组患者术后6 h的血清D-乳酸含量较术前6 h明显升高(P<0.05);与L组比较,M组和H组术后6 h的血清D-乳酸含量明显升高(P<0.05)。三组患者PaO2差异无统计学意义。与L组比较,T3、T4时M组和H组pH明显降低(P<0.05);T3~T5时M组和H组PaCO2明显升高(P<0.05)。与L组比较,M组和H组的患者首次排气时间、进食时间、排便时间及术后住院时间明显延长(P<0.05)。结论 低CO2压力气腹可减轻CO2气腹对患者胃肠道功能的损伤,有利于患者术后早期胃肠道功能的恢复。
英文摘要:
      Objective To investigate the effect of different pressure CO2 pneumoperitoneum on postoperative gastroeuteric function in female patients undergoing gynecological laparoscopic surgery. Methods A total of 120 female patients, aged 30-60 years, ASA physical status Ⅰ or Ⅱ, scheduled for elective gynecological laparoscopic surgery were randomly into three groups (n=40 in each). The pressure of CO2pneumoperitoneum were set at 6-8, 9-11 and 12-14 mm Hg in group L, group M and group H, respectively. All patients were detected on an empty stomach of serum concentrations of D-lactic acid 6 hours before operation and after opration. In addition, pH, PaCO2 and PaO2 were recorded before anesthesia (T1), before pneumoperitoneum (T2), 1 hour after pneumoperitoneum (T3) 2 hours after pneumoperitoneum (T4) and 1 hour (T5) after stopping pneumoperitoneum. The time of pneumoperitoneum, the time of first flatus, intake and defecation, length of primary hospital stays after operation were recorded. Results Compared with 6 hours before operation, the serum concentrations of D-lactic acid were obviously increased at postoperative 6 hours in all groups (P<0.05). Compared with group L, the serum concentrations of D-lactic acid at 6 hours after operation were obviously increased in group M and group H (P<0.05). PaO2 in three groups was not different at T1-T5. Compared with group L, pH at T3, T4 was significantly decreased in group M and group H (P<0.05). Compared with group L, PaCO2 was significantly increased at T3-T5 in group M and group H (P<0.05). Compared with group L, the time of first flatus, intake and defecation, length of primary hospital stays after operation were obviously delayed in group M and group H(P<0.05). Conclusion The low pressure of CO2pneumoperitoneum can reduce the damage of CO2 pneumoperitoneum on postoperative gastroeuteric function and avail the recovery of parents’ postoperative gastroeutericfunction in female patients undergoing gynecological laparoscopic surgery.
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