文章摘要
中老年手术患者右颈动脉斑块的危险因素分析
Risk factor analysis of carotid plaque in the right carotid in the middle-age and elderly surgical patients
  
DOI:
中文关键词: 颈内静脉  颈动脉  斑块  危险因素
英文关键词: Central vein  Carotid  Plaque  Risk factors
基金项目:
作者单位
何毅 510080 广东省心血管病研究所广东省人民医院广东省医学科学院麻醉科 
王晟 510080 广东省心血管病研究所广东省人民医院广东省医学科学院麻醉科 
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中文摘要:
      目的:观察中老年择期手术患者右侧颈动脉斑块发生率、位置及性质,探讨其发生的独立危险因素。方法选择中老年择期手术患者738例,年龄40~78岁,ASA Ⅰ~Ⅲ级,右侧颈部无血肿、破溃或中心静脉置管,行右侧颈动脉超声检查,按是否观察到颈动脉斑块,将患者分为斑块组(PW 组)及非斑块组(NPW 组),并采集相关病史,记录颈动脉斑块的发生率、位置和性质分布,分析颈动脉斑块发生的危险因素。结果颈动脉斑块的发生率为194例(26.3%)(PW 组),PW 组中斑块的发生位置分布:高位斑块148例(76.3%),中位斑块124例(63.9%),低位斑块48例(24.7%);斑块的性质分布:软斑16例(8%),硬斑88例(45.4%),混合斑98例(50.5%)。年龄、高血压史、冠心病史、高脂血症史、糖尿病史及吸烟史为颈动脉斑块发生的独立危险因素(P <0.05)。结论年龄、高血压史、冠心病史、高脂血症史、糖尿病史及吸烟史与颈动脉斑块发生相关。患者颈动脉斑块高发部位为颈膨大处至环状软骨平面之间,斑块性质以不稳定斑块为主。
英文摘要:
      Objective To evaluate the risk factors of carotid plaque,in which middle-age and elderly patients undergoing selective surgery,via observation of proportions and properties of plaques. Methods ASA Ⅰ-Ⅲ patients of 738,aged 40-78 years,undergoing selective surgery,requiring no hematoma,ulceration or CVP catheter on right side of neck,were examined by ultrasonography.The location and properties of the discoverable carotid plaque were recorded.According to occurrence of carotid plaque,patients were divided into plaque observed group (group PW)and plaque not observed group (group NPW).The information of patients’age,gender,BMI,history of hypertension,diabe-tes, coronary disease, hyperlipidemia and smoking were also collected for further analysis. Results Carotid plaques were observed in 1 94 patients (26.3%)(group PW).In PW group,upper plaques were found in 148 patients (76.3%),middle plaques in 124 patients (63.9%)and lower plaques in 48 patients (24.7%);soft plaque n = 1 6 (8%),hard plaque n = 88 (45.4%)and mixed plaque n =98 (50.5%).Age,BMI,diastolic pressure,history of hypertension,hyperlipidemia,dia-betes,coronary disease and smoking were the independent risk factors (P <0.05).Conclusion Age, history of hypertension,hyperlipidemia,diabetes,coronary disease and smoking were the correlation factors with plaques formation.Carotid plaques were mainly unstable and observed between the plane of cervical enlargement and cricoid cartilage.
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