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| 瑞马唑仑与术后早期临床结局 |
| Remimazolam and postoperative early outcomes |
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| DOI：10.12089/jca.2026.08.014 |
| 中文关键词: 瑞马唑仑 谵妄 术后恶心呕吐 睡眠质量 恢复质量 |
| 英文关键词: Remimazolam Delirium Postoperative nausea and vomiting Sleep quality Quality of recovery |
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| 中文摘要: |
| 瑞马唑仑是一种超短效苯二氮?类药物，具有起效快、恢复快、对肝肾功能影响小等优势，目前已经广泛应用于围术期镇静和全身麻醉。瑞马唑仑麻醉后的恶心呕吐发生率较低，采用瑞马唑仑维持麻醉或单次给予瑞马唑仑可以降低患儿苏醒期谵妄和术后谵妄的发生率，且瑞马唑仑不升高成年患者术后谵妄的发生率。瑞马唑仑对术后睡眠质量和恢复质量的影响尚不确定。本文对瑞马唑仑与术后1周内临床结局相关性的研究进行综述。 |
| 英文摘要: |
| Remimazolam is an ultra-short-acting benzodiazepine which presents advantages in rapid onset, fast recovery, and minimal impact on hepatic and renal function. It has been widely used for perioperative sedation and general anesthesia. Remimazolam anesthesia was associated with lower incidence of postoperative nausea and vomiting. Remimazolam anesthesia or a single bolus of remimazolam before the end of general anesthesia could decrease the risk of emergence delirium and postoperative delirium in surgical pediatrics. Remimazolam did not increase the risk of postoperative delirium in adult patients. There was insufficient data to support the effect of remimazolam on postoperative sleep quality and quality of recovery. This article reviews the relationship between remimazolam and early clinical outcomes within one week postoperatively. |
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