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| 全身麻醉术后睡眠障碍的影响因素和治疗进展 |
| Influencing factors of postoperative sleep disturbance under general anesthesia and treatment progress |
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| DOI：10.12089/jca.2026.07.011 |
| 中文关键词: 术后睡眠障碍 影响因素 疼痛 麻醉药物 治疗 |
| 英文关键词: Postoperative sleep disturbances Influencing factors Pain Anesthetic drugs Treatment |
| 基金项目:国家自然科学基金面上项目（82171205）；国家自然科学基金青年科学基金项目（81801107） |
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| 中文摘要: |
| 术后睡眠障碍是手术后的常见并发症，与术后疼痛、炎症反应、麻醉药物、患者基础情况、病房环境等诸多影响因素有关。术后睡眠障碍可导致神经内分泌失衡，不仅延缓伤口愈合、削弱免疫功能，还与术后谵妄及慢性疼痛的发生密切相关。近年来，除了优化镇痛方案，围术期预防性使用如右美托咪定等具有睡眠调节作用的药物以及经皮穴位电刺激等非药物治疗手段，显示出良好的应用前景。因此，系统识别相关危险因素并采取针对性预防策略，对于改善患者预后至关重要。本文旨在综述术后睡眠障碍的影响机制与治疗干预研究进展，以期为优化围术期睡眠管理提供依据与参考。 |
| 英文摘要: |
| Postoperative sleep disturbance (PSD) is a common surgical complication influenced by pain, inflammation, anesthetics, comorbidities, and environmental factors. PSD induces neuroendocrine imbalance, impairing wound healing and immune function while increasing risks of delirium and chronic pain. In recent years, beyond optimizing analgesic protocols, the perioperative prophylactic use of drugs with sleep-regulating properties like dexmedetomidine, as well as non-pharmacological interventions such as transcutaneous electrical acupoint stimulation, has shown promising application potential. Systematic risk identification and targeted prevention are thus vital for improving outcomes. This review summarizes recent advances in the mechanisms and therapeutic interventions for PSD, aiming to provide evidence and reference for optimizing perioperative sleep management. |
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