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| 围术期神经认知障碍早期诊断的研究进展 |
| Research advances in early diagnosis of perioperative neurocognitive disorders |
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| DOI：10.12089/jca.2025.11.014 |
| 中文关键词: 神经认知功能障碍 早期诊断 神经心理学量表 生物学标记物 神经影像学 |
| 英文关键词: Neurocognitive dysfunction Early diagnosis Neuropsychological testing Biological markers Neuroimaging |
| 基金项目:国家自然科学基金面上项目（82271231）；国家口腔疾病临床医学研究中心专项课题（LCB202413） |
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| 中文摘要: |
| 围术期神经认知障碍（PND）是老年患者围术期常见的并发症之一，其特征是患者认知功能下降、记忆受损及注意力不能集中。PND的发生将会延长患者住院时间，增加就医成本。因此，早期诊断PND对于及时干预病情发展、提高患者就医质量具有重要的意义。本文系统地综述了PND的早期诊断方法，分析了目前常用的神经心理学量表、生物学标记物以及神经影像学在PND早期诊断中的作用，探讨了PND早期诊断可能的发展方向，为提高PND早期诊断的准确性提供参考。 |
| 英文摘要: |
| Perioperative neurocognitive disorders (PND), one of the most prevalent complications among elderly patients during the perioperative period, are characterized by cognitive decline, memory impairment, and attention deficits. The occurrence of PND will prolong the hospital stay of patients, increase the cost of medical treatment. Therefore, early diagnosis of PND is of great significance for timely intervention in the development of the disease and improvement of the quality of patients medical treatment. This paper systematically reviews the early diagnosis methods of PND, analyses the role of neuropsychological scales, biological markers and neuroimaging in the early diagnosis of PND, and discusses the possible development direction of the early diagnosis of PND in the future, in order to provide a reference for improving the accuracy of early diagnosis of PND. |
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